Mutations in the C-terminus of HBoV NS1 affect the function of NP1
Mutations in the C-terminus of HBoV NS1 affect the function of NP1
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Author / Creator
Zhang, Junmei , Bai, Yan , Zhu, Bing , Hao, Sujuan , Chen, Zhen , Wang, Hanzhong and Guan, Wuxiang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Human bocavirus 1 (HBoV1) is an autonomous parvovirus in the
Bocaparvovirus
genus. The multifunctional nuclear protein NP1 is involved in viral replication. In the present study, we found that the mutations in the C-terminus of NS1 affected NP1 function in viral replication. Knocking out NP1 expression in the recombinant infectious clone, on...
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Full title
Mutations in the C-terminus of HBoV NS1 affect the function of NP1
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4c9ae7e602524ea99bc6368ba0148dc2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c9ae7e602524ea99bc6368ba0148dc2
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-06513-4