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Mutations in the C-terminus of HBoV NS1 affect the function of NP1

Mutations in the C-terminus of HBoV NS1 affect the function of NP1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c9ae7e602524ea99bc6368ba0148dc2

Mutations in the C-terminus of HBoV NS1 affect the function of NP1

About this item

Full title

Mutations in the C-terminus of HBoV NS1 affect the function of NP1

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-08, Vol.7 (1), p.7407-12, Article 7407

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Human bocavirus 1 (HBoV1) is an autonomous parvovirus in the
Bocaparvovirus
genus. The multifunctional nuclear protein NP1 is involved in viral replication. In the present study, we found that the mutations in the C-terminus of NS1 affected NP1 function in viral replication. Knocking out NP1 expression in the recombinant infectious clone, on...

Alternative Titles

Full title

Mutations in the C-terminus of HBoV NS1 affect the function of NP1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4c9ae7e602524ea99bc6368ba0148dc2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c9ae7e602524ea99bc6368ba0148dc2

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-06513-4

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