mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 med...
mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A
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Author / Creator
Zhao, Liang , Su, Huizhao , Liu, Xiaomeng , Wang, Hongquan , Feng, Yukuan , Wang, Yan , Chen, Haiqiang , Dai, Luo , Lai, Shihui , Xu, Siqi , Li, Chong , Hao, Jihui and Tang, Bo
Publisher
London: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
London: BioMed Central Ltd
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Scope and Contents
Contents
Exploiting cancer metabolism during nutrient availability holds immense potential for the clinical and therapeutic benefits of hepatocellular carcinoma (HCC) patients. Dietary methionine is a metabolic dependence of cancer development, but how the signal transduction integrates methionine status to achieve the physiological demand of cancer cells r...
Alternative Titles
Full title
mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4ca65426cb19414cb3d06183ae93c4b7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4ca65426cb19414cb3d06183ae93c4b7
Other Identifiers
ISSN
2045-3701
E-ISSN
2045-3701
DOI
10.1186/s13578-022-00919-y
