SCADIE: simultaneous estimation of cell type proportions and cell type-specific gene expressions usi...
SCADIE: simultaneous estimation of cell type proportions and cell type-specific gene expressions using SCAD-based iterative estimating procedure
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Scope and Contents
Contents
A challenge in bulk gene differential expression analysis is to differentiate changes due to cell type-specific gene expression and cell type proportions. SCADIE is an iterative algorithm that simultaneously estimates cell type-specific gene expression profiles and cell type proportions, and performs cell type-specific differential expression analy...
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Full title
SCADIE: simultaneous estimation of cell type proportions and cell type-specific gene expressions using SCAD-based iterative estimating procedure
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4cd911f4fe6e49b5980bfcd54d792518
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4cd911f4fe6e49b5980bfcd54d792518
Other Identifiers
ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-022-02688-w
