EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax an...
EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV-1-infected individuals, irrespective of clinical statuses
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
EOS plays an important role in maintaining the suppressive function of regulatory T cells (Tregs), and induces a regulated transformation of Tregs into T helper-like cells, which are capable of secreting proinflammatory cytokines in response to specific inflammatory signals. Meanwhile, significant reduction in Treg activity along with production of...
Alternative Titles
Full title
EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV-1-infected individuals, irrespective of clinical statuses
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TN_cdi_doaj_primary_oai_doaj_org_article_4d155d85979e4401a5412b7f895f4a94
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4d155d85979e4401a5412b7f895f4a94
Other Identifiers
ISSN
1743-422X
E-ISSN
1743-422X
DOI
10.1186/s12985-019-1270-1
