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Leveraging multiple data types for improved compound-kinase bioactivity prediction

Leveraging multiple data types for improved compound-kinase bioactivity prediction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4d18f6b76b8e4d209b0b977e65748d7a

Leveraging multiple data types for improved compound-kinase bioactivity prediction

About this item

Full title

Leveraging multiple data types for improved compound-kinase bioactivity prediction

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-08, Vol.15 (1), p.7596-12, Article 7596

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Machine learning provides efficient ways to map compound-kinase interactions. However, diverse bioactivity data types, including single-dose and multi-dose-response assay results, present challenges. Traditional models utilize only multi-dose data, overlooking information contained in single-dose measurements. Here, we propose a machine learning me...

Alternative Titles

Full title

Leveraging multiple data types for improved compound-kinase bioactivity prediction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4d18f6b76b8e4d209b0b977e65748d7a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4d18f6b76b8e4d209b0b977e65748d7a

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-52055-5

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