iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric can...
iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer
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Author / Creator
Ding, Naiqing , Zou, Zhengyun , Sha, Huizi , Su, Shu , Qian, Hanqing , Meng, Fanyan , Chen, Fangjun , Du, Shiyao , Zhou, Shujuan , Chen, Hong , Zhang, Lianru , Yang, Ju , Wei, Jia and Liu, Baorui
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Poor infiltration of activated lymphocytes into tumors represents a fundamental factor limiting the therapeutic effect of adoptive cell immunotherapy. A tumor-penetrating peptide, iRGD, has been widely used to deliver drugs into tumor tissues. In this study, we demonstrate for the first time that iRGD could also facilitate the infiltration of lymph...
Alternative Titles
Full title
iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4d424ce982544f98bbf28d7feda3ba49
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4d424ce982544f98bbf28d7feda3ba49
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09296-6
