Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function
Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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The T cell antigen coupler (TAC) receptor is a novel synthetic receptor designed to maximize the therapeutic potential of T cells in the absence of tonic signaling or receptor-related toxicities. Prior studies indicated that TACs provide safe and long-lasting anti-tumor immunity in multiple preclinical models of solid tumors supported by mounting c...
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Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function
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TN_cdi_doaj_primary_oai_doaj_org_article_4d7b5b17a9bb4b8f9a2d6ff6b27d2f84
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4d7b5b17a9bb4b8f9a2d6ff6b27d2f84
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-87944-2
