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Human induced pluripotent stem cell-derived myotubes to model inclusion body myositis

Human induced pluripotent stem cell-derived myotubes to model inclusion body myositis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4dd777091c6e4188a2e33991830a2832

Human induced pluripotent stem cell-derived myotubes to model inclusion body myositis

About this item

Full title

Human induced pluripotent stem cell-derived myotubes to model inclusion body myositis

Publisher

England: BioMed Central Ltd

Journal title

Acta neuropathologica communications, 2025-02, Vol.13 (1), p.38-18, Article 38

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Inclusion body myositis (IBM) is an inflammatory myopathy that displays proximal and distal muscle weakness. At the histopathological level, the muscles of IBM patients show inflammatory infiltrates, rimmed vacuoles and mitochondrial changes. The etiology of IBM remains unknown, and there is a lack of validated disease models, biomarkers and effect...

Alternative Titles

Full title

Human induced pluripotent stem cell-derived myotubes to model inclusion body myositis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4dd777091c6e4188a2e33991830a2832

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4dd777091c6e4188a2e33991830a2832

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-025-01933-0

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