A Novel Hydrogen Sulfide Donor Reduces Pilocarpine-Induced Status Epilepticus and Regulates Microgli...
A Novel Hydrogen Sulfide Donor Reduces Pilocarpine-Induced Status Epilepticus and Regulates Microglial Inflammatory Profile
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Author / Creator
Liu, Zhongrui , Zhu, Ziting , He, Yan , Kang, Qiyun , Li, Fei , Zhang, Wenlong , He, Yuehua , Lin, Yuwan , Huang, Baoyi , Mo, Mingshu , Xu, Pingyi and Zhu, Xiaoqin
Publisher
Switzerland: Frontiers Research Foundation
Journal title
Language
English
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Publication information
Publisher
Switzerland: Frontiers Research Foundation
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Contents
Although epilepsy is one of the most common neurologic disorders, there is still a lack of effective therapeutic drugs for it. Recently, we synthesized a novel hydrogen sulfide (H
2
S) donor, which is found to reduce seizures in animal models effectively. But it remains to be determined for its mechanism. In the present study, we found that t...
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Full title
A Novel Hydrogen Sulfide Donor Reduces Pilocarpine-Induced Status Epilepticus and Regulates Microglial Inflammatory Profile
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TN_cdi_doaj_primary_oai_doaj_org_article_4deb0b1dea884317bb4c24f270ce7f5a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4deb0b1dea884317bb4c24f270ce7f5a
Other Identifiers
ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2021.780447
