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TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration foll...

TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration foll...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4df2d75b2641495eaec192da38620eb9

TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration following retinal detachment

About this item

Full title

TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration following retinal detachment

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2023-03, Vol.14 (3), p.219-219, Article 219

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Retinal detachment (RD) occurs in several major retinal conditions and often causes irreversible vision loss due to photoreceptor cell death. Retinal residential microglial cells are activated following RD and participate in photoreceptor cell death via direct phagocytosis and the regulation of inflammatory responses. Triggering receptor expressed...

Alternative Titles

Full title

TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration following retinal detachment

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4df2d75b2641495eaec192da38620eb9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4df2d75b2641495eaec192da38620eb9

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-023-05735-x

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