TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration foll...
TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration following retinal detachment
About this item
Full title
Author / Creator
Zhou, Wenchuan , Zhou, Yutong , He, Jincan , Rao, Yuqing , Fei, Ping and Li, Jing
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Retinal detachment (RD) occurs in several major retinal conditions and often causes irreversible vision loss due to photoreceptor cell death. Retinal residential microglial cells are activated following RD and participate in photoreceptor cell death via direct phagocytosis and the regulation of inflammatory responses. Triggering receptor expressed...
Alternative Titles
Full title
TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration following retinal detachment
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Author / Creator
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TN_cdi_doaj_primary_oai_doaj_org_article_4df2d75b2641495eaec192da38620eb9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4df2d75b2641495eaec192da38620eb9
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-023-05735-x