A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity
A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity
About this item
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Author / Creator
Fagnocchi, Luca , Cherubini, Alessandro , Hatsuda, Hiroshi , Fasciani, Alessandra , Mazzoleni, Stefania , Poli, Vittoria , Berno, Valeria , Rossi, Riccardo L. , Reinbold, Rolland , Endele, Max , Schroeder, Timm , Rocchigiani, Marina , Szkarłat, Żaneta , Oliviero, Salvatore , Dalton, Stephen and Zippo, Alessio
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Stem cell identity depends on the integration of extrinsic and intrinsic signals, which directly influence the maintenance of their epigenetic state. Although Myc transcription factors play a major role in stem cell self-renewal and pluripotency, their integration with signalling pathways and epigenetic regulators remains poorly defined. We address...
Alternative Titles
Full title
A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4dfc9facb00e4f1c81f05614a3a4b0b2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4dfc9facb00e4f1c81f05614a3a4b0b2
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11903
