Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration
Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Muscular dystrophies are severe disorders due to mutations in structural genes, and are characterized by skeletal muscle wasting, compromised patient mobility, and respiratory functions. Although previous works suggested enhancing regeneration and muscle mass as therapeutic strategies, these led to no long-term benefits in humans. Mice lacking the...
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Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration
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TN_cdi_doaj_primary_oai_doaj_org_article_4dfcc452d0b14567b01bb5bcd9666918
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4dfcc452d0b14567b01bb5bcd9666918
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01098-y