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Assessing agreement between different polygenic risk scores in the UK Biobank

Assessing agreement between different polygenic risk scores in the UK Biobank

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4e1eeb4a061f41ef85a40e780467bb67

Assessing agreement between different polygenic risk scores in the UK Biobank

About this item

Full title

Assessing agreement between different polygenic risk scores in the UK Biobank

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-07, Vol.12 (1), p.12812-8, Article 12812

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Polygenic risk scores (PRS) are proposed for use in clinical and research settings for risk stratification. However, there are limited investigations on how different PRS diverge from each other in risk prediction of individuals. We compared two recently published PRS for each of three conditions, breast cancer, hypertension and dementia, to assess...

Alternative Titles

Full title

Assessing agreement between different polygenic risk scores in the UK Biobank

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4e1eeb4a061f41ef85a40e780467bb67

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4e1eeb4a061f41ef85a40e780467bb67

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-17012-6

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