Cerebrospinal fluid N-224 tau helps discriminate Alzheimer’s disease from subjective cognitive decli...
Cerebrospinal fluid N-224 tau helps discriminate Alzheimer’s disease from subjective cognitive decline and other dementias
About this item
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Author / Creator
Cicognola, Claudia , Hansson, Oskar , Scheltens, Philip , Kvartsberg, Hlin , Zetterberg, Henrik , Teunissen, Charlotte E. , Blennow, Kaj , Faculty of Medicine , Medicinska fakulteten , Strategiska forskningsområden (SFO) , Institutionen för kliniska vetenskaper, Malmö , Clinical Memory Research , Strategic research areas (SRA) , Lunds universitet , Klinisk minnesforskning , Profilområden och andra starka forskningsmiljöer , Lund University , MultiPark: Multidisciplinary research focused on Parkinson´s disease , Profile areas and other strong research environments and Department of Clinical Sciences, Malmö
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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More information
Scope and Contents
Contents
Elevated cerebrospinal fluid (CSF) concentrations of total tau (T-tau) and phosphorylated tau at Thr181 (P-tau181) protein are typical of Alzheimer's disease (AD). However, the T-tau assay measures only the mid-region of the protein, while tau in CSF is instead composed of a series of fragments. One fragment species in particular, N-224, shows incr...
Alternative Titles
Full title
Cerebrospinal fluid N-224 tau helps discriminate Alzheimer’s disease from subjective cognitive decline and other dementias
Authors, Artists and Contributors
Author / Creator
Hansson, Oskar
Scheltens, Philip
Kvartsberg, Hlin
Zetterberg, Henrik
Teunissen, Charlotte E.
Blennow, Kaj
Faculty of Medicine
Medicinska fakulteten
Strategiska forskningsområden (SFO)
Institutionen för kliniska vetenskaper, Malmö
Clinical Memory Research
Strategic research areas (SRA)
Lunds universitet
Klinisk minnesforskning
Profilområden och andra starka forskningsmiljöer
Lund University
MultiPark: Multidisciplinary research focused on Parkinson´s disease
Profile areas and other strong research environments
Department of Clinical Sciences, Malmö
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4e83b8214c8546bd974433f15c71d8fa
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4e83b8214c8546bd974433f15c71d8fa
Other Identifiers
ISSN
1758-9193
E-ISSN
1758-9193
DOI
10.1186/s13195-020-00756-6
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