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Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann–Pick disease t...

Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann–Pick disease t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4e90738b28c44e4c9ddaf53a1c5805b3

Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann–Pick disease type C treatment

About this item

Full title

Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann–Pick disease type C treatment

Publisher

Heidelberg: John Wiley & Sons, Inc

Journal title

Clinical and Translational Medicine, 2023-08, Vol.13 (8), p.e1350-n/a

Language

English

Formats

Publication information

Publisher

Heidelberg: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Background
Niemann–Pick disease type C (NPC) is a fatal neurodegenerative disorder caused by abnormal intracellular cholesterol trafficking. Cyclodextrins (CDs), the most promising therapeutic candidates for NPC, but with concerns about ototoxicity, are cyclic oligosaccharides with dual functions of unesterified cholesterol (UC) shuttle and sink...

Alternative Titles

Full title

Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann–Pick disease type C treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4e90738b28c44e4c9ddaf53a1c5805b3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4e90738b28c44e4c9ddaf53a1c5805b3

Other Identifiers

ISSN

2001-1326

E-ISSN

2001-1326

DOI

10.1002/ctm2.1350

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