Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cel...
Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival
About this item
Full title
Author / Creator
Guilhamon, Paul , Chesnelong, Charles , Kushida, Michelle M , Nikolic, Ana , Singhal, Divya , MacLeod, Graham , Madani Tonekaboni, Seyed Ali , Cavalli, Florence MG , Arlidge, Christopher , Rajakulendran, Nishani , Rastegar, Naghmeh , Hao, Xiaoguang , Hassam, Rozina , Smith, Laura J , Whetstone, Heather , Coutinho, Fiona J , Nadorp, Bettina , Ellestad, Katrina I , Luchman, H Artee , Chan, Jennifer Ai-wen , Shoichet, Molly S , Taylor, Michael D , Haibe-Kains, Benjamin , Weiss, Samuel , Angers, Stephane , Gallo, Marco , Dirks, Peter B and Lupien, Mathieu
Publisher
England: eLife Science Publications, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Science Publications, Ltd
Subjects
More information
Scope and Contents
Contents
Chromatin accessibility discriminates stem from mature cell populations, enabling the identification of primitive stem-like cells in primary tumors, such as glioblastoma (GBM) where self-renewing cells driving cancer progression and recurrence are prime targets for therapeutic intervention. We show, using single-cell chromatin accessibility, that p...
Alternative Titles
Full title
Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival
Authors, Artists and Contributors
Author / Creator
Chesnelong, Charles
Kushida, Michelle M
Nikolic, Ana
Singhal, Divya
MacLeod, Graham
Madani Tonekaboni, Seyed Ali
Cavalli, Florence MG
Arlidge, Christopher
Rajakulendran, Nishani
Rastegar, Naghmeh
Hao, Xiaoguang
Hassam, Rozina
Smith, Laura J
Whetstone, Heather
Coutinho, Fiona J
Nadorp, Bettina
Ellestad, Katrina I
Luchman, H Artee
Chan, Jennifer Ai-wen
Shoichet, Molly S
Taylor, Michael D
Haibe-Kains, Benjamin
Weiss, Samuel
Angers, Stephane
Gallo, Marco
Dirks, Peter B
Lupien, Mathieu
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4edd65e2fbd64b6d96f15edad9ae3485
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4edd65e2fbd64b6d96f15edad9ae3485
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.64090
