CLDN6 inhibits breast cancer growth and metastasis through SREBP1-mediated RAS palmitoylation
CLDN6 inhibits breast cancer growth and metastasis through SREBP1-mediated RAS palmitoylation
About this item
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Author / Creator
Jin, Qiu , Qi, Da , Zhang, Mingzi , Qu, Huinan , Dong, Yuan , Sun, Minghao and Quan, Chengshi
Publisher
England: BioMed Central
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central
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Scope and Contents
Contents
Breast cancer (BC) ranks as the third most fatal malignant tumor worldwide, with a strong reliance on fatty acid metabolism. CLDN6, a candidate BC suppressor gene, was previously identified as a regulator of fatty acid biosynthesis; however, the underlying mechanism remains elusive. In this research, we aim to clarify the specific mechanism through...
Alternative Titles
Full title
CLDN6 inhibits breast cancer growth and metastasis through SREBP1-mediated RAS palmitoylation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4efe1a97eb60427aa817c80b7246b5c7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4efe1a97eb60427aa817c80b7246b5c7
Other Identifiers
ISSN
1689-1392,1425-8153
E-ISSN
1689-1392
DOI
10.1186/s11658-024-00629-y
