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A proof-of-concept study in small and large animal models for coupling liver normothermic machine pe...

A proof-of-concept study in small and large animal models for coupling liver normothermic machine pe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f06d0f4c0a6411ca0c0f3a26ebd018f

A proof-of-concept study in small and large animal models for coupling liver normothermic machine perfusion with mesenchymal stromal cell bioreactors

About this item

Full title

A proof-of-concept study in small and large animal models for coupling liver normothermic machine perfusion with mesenchymal stromal cell bioreactors

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2025-01, Vol.16 (1), p.283-14, Article 283

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

To fully harness mesenchymal-stromal-cells (MSCs)’ benefits during Normothermic Machine Perfusion (NMP), we developed an advanced NMP platform coupled with a MSC-bioreactor and investigated its bio-molecular effects and clinical feasibility using rat and porcine models. The study involved three work packages: 1) Development (
n
 = 5): MSC-bio...

Alternative Titles

Full title

A proof-of-concept study in small and large animal models for coupling liver normothermic machine perfusion with mesenchymal stromal cell bioreactors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4f06d0f4c0a6411ca0c0f3a26ebd018f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f06d0f4c0a6411ca0c0f3a26ebd018f

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-55217-7

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