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Obesity-induced inflammation exacerbates clonal hematopoiesis

Obesity-induced inflammation exacerbates clonal hematopoiesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f0b42d1f8824ea3ade0118083a7178c

Obesity-induced inflammation exacerbates clonal hematopoiesis

About this item

Full title

Obesity-induced inflammation exacerbates clonal hematopoiesis

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2023-06, Vol.133 (11)

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Characterized by the accumulation of somatic mutations in blood cell lineages, clonal hematopoiesis of indeterminate potential (CHIP) is frequent in aging and involves the expansion of mutated hematopoietic stem and progenitor cells (HSC/Ps) that leads to an increased risk of hematologic malignancy. However, the risk factors that contribute to CHIP...

Alternative Titles

Full title

Obesity-induced inflammation exacerbates clonal hematopoiesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4f0b42d1f8824ea3ade0118083a7178c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f0b42d1f8824ea3ade0118083a7178c

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI163968

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