Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer
Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer
About this item
Full title
Author / Creator
Cao, Liwei , Pauthner, Matthias , Andrabi, Raiees , Rantalainen, Kimmo , Berndsen, Zachary , Diedrich, Jolene K. , Menis, Sergey , Sok, Devin , Bastidas, Raiza , Park, Sung-Kyu Robin , Delahunty, Claire M. , He, Lin , Guenaga, Javier , Wyatt, Richard T. , Schief, William R. , Ward, Andrew B. , Yates, John R. , Burton, Dennis R. and Paulson, James C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
As the sole target of broadly neutralizing antibodies (bnAbs) to HIV, the envelope glycoprotein (Env) trimer is the focus of vaccination strategies designed to elicit protective bnAbs in humans. Because HIV Env is densely glycosylated with 75–90 N-glycans per trimer, most bnAbs use or accommodate them in their binding epitope, making the glycosylat...
Alternative Titles
Full title
Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer
Authors, Artists and Contributors
Author / Creator
Pauthner, Matthias
Andrabi, Raiees
Rantalainen, Kimmo
Berndsen, Zachary
Diedrich, Jolene K.
Menis, Sergey
Sok, Devin
Bastidas, Raiza
Park, Sung-Kyu Robin
Delahunty, Claire M.
He, Lin
Guenaga, Javier
Wyatt, Richard T.
Schief, William R.
Ward, Andrew B.
Yates, John R.
Burton, Dennis R.
Paulson, James C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4f20b420b7274e21b3fd2be2a1aa131b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f20b420b7274e21b3fd2be2a1aa131b
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06121-4
