Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair
Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair
About this item
Full title
Author / Creator
Li, Shen , Yokota, Tomohiro , Wang, Ping , Ten Hoeve, Johanna , Ma, Feiyang , Le, Thuc M , Abt, Evan R , Zhou, Yonggang , Wu, Rimao , Nanthavongdouangsy, Maxine , Rodriguez, Abraham , Wang, Yijie , Lin, Yen-Ju , Muranaka, Hayato , Sharpley, Mark , Braddock, Demetrios T , MacRae, Vicky E , Banerjee, Utpal , Chiou, Pei-Yu , Seldin, Marcus , Huang, Dian , Teitell, Michael , Gertsman, Ilya , Jung, Michael , Bensinger, Steven J , Damoiseaux, Robert , Faull, Kym , Pellegrini, Matteo , Lusis, Aldons J , Graeber, Thomas G , Radu, Caius G and Deb, Arjun
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Various populations of cells are recruited to the heart after cardiac injury, but little is known about whether cardiomyocytes directly regulate heart repair. Using a murine model of ischemic cardiac injury, we demonstrate that cardiomyocytes play a pivotal role in heart repair by regulating nucleotide metabolism and fates of nonmyocytes. Cardiac i...
Alternative Titles
Full title
Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair
Authors, Artists and Contributors
Author / Creator
Yokota, Tomohiro
Wang, Ping
Ten Hoeve, Johanna
Ma, Feiyang
Le, Thuc M
Abt, Evan R
Zhou, Yonggang
Wu, Rimao
Nanthavongdouangsy, Maxine
Rodriguez, Abraham
Wang, Yijie
Lin, Yen-Ju
Muranaka, Hayato
Sharpley, Mark
Braddock, Demetrios T
MacRae, Vicky E
Banerjee, Utpal
Chiou, Pei-Yu
Seldin, Marcus
Huang, Dian
Teitell, Michael
Gertsman, Ilya
Jung, Michael
Bensinger, Steven J
Damoiseaux, Robert
Faull, Kym
Pellegrini, Matteo
Lusis, Aldons J
Graeber, Thomas G
Radu, Caius G
Deb, Arjun
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4f249dd668874f6a904b120bd8b43144
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f249dd668874f6a904b120bd8b43144
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI149711
