MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expr...
MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Hedgehog (Hh) signalling regulates hepatic fibrogenesis. MicroRNAs (miRNAs) mediate various cellular processes; however, their role in liver fibrosis is unclear. Here we investigate regulation of miRNAs in chronically damaged fibrotic liver. MiRNA profiling shows that expression of miR-378 family members (miR-378a-3p, miR-378b and miR-378d) decline...
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MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression
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TN_cdi_doaj_primary_oai_doaj_org_article_4f54381c8f96469a82e5f4d6d35090c7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f54381c8f96469a82e5f4d6d35090c7
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10993