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MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expr...

MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f54381c8f96469a82e5f4d6d35090c7

MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression

About this item

Full title

MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2016-03, Vol.7 (1), p.10993-10993, Article 10993

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hedgehog (Hh) signalling regulates hepatic fibrogenesis. MicroRNAs (miRNAs) mediate various cellular processes; however, their role in liver fibrosis is unclear. Here we investigate regulation of miRNAs in chronically damaged fibrotic liver. MiRNA profiling shows that expression of miR-378 family members (miR-378a-3p, miR-378b and miR-378d) decline...

Alternative Titles

Full title

MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4f54381c8f96469a82e5f4d6d35090c7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f54381c8f96469a82e5f4d6d35090c7

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms10993

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