Letrozole protects against cadmium-induced inhibition of spermatogenesis via LHCGR and Hsd3b6 to act...
Letrozole protects against cadmium-induced inhibition of spermatogenesis via LHCGR and Hsd3b6 to activate testosterone synthesis in mice
About this item
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Author / Creator
Yao, Yao , Wan, Yangyang , Shi, Xiaoyun , Guo, Lan , Jiang, Hui , Zhang, Xiansheng , Xu, Bo and Hua, Juan
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The heavy metal cadmium is proposed to be one of the environmental endocrine disruptors of spermatogenesis. Cadmium-induced inhibition of spermatogenesis is associated with a hormone secretion disorder. Letrozole is an aromatase inhibitor that increases peripheral androgen levels and stimulates spermatogenesis. However, the potential protective eff...
Alternative Titles
Full title
Letrozole protects against cadmium-induced inhibition of spermatogenesis via LHCGR and Hsd3b6 to activate testosterone synthesis in mice
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4f7f621ac60e4827bd0fa866aeae1ecd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f7f621ac60e4827bd0fa866aeae1ecd
Other Identifiers
ISSN
1477-7827
E-ISSN
1477-7827
DOI
10.1186/s12958-022-00915-4
