Ensemble-Based Virtual Screening Led to the Discovery of Novel Lead Molecules as Potential NMBAs
Ensemble-Based Virtual Screening Led to the Discovery of Novel Lead Molecules as Potential NMBAs
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Author / Creator
Zhang, Yi , Ge, Gonghui , Xu, Xiangyang and Wu, Jinhui
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Neuromuscular blocking agents (NMBAs) are routinely used during anesthesia to relax skeletal muscle. Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels; NMBAs can induce muscle paralysis by preventing the neurotransmitter acetylcholine (ACh) from binding to nAChRs situated on the postsynaptic membranes. Despite widespread effo...
Alternative Titles
Full title
Ensemble-Based Virtual Screening Led to the Discovery of Novel Lead Molecules as Potential NMBAs
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Author / Creator
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TN_cdi_doaj_primary_oai_doaj_org_article_4f9b23cdd8fd4f1884272bd9190f9085
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4f9b23cdd8fd4f1884272bd9190f9085
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules29091955
