Unexpected sequences and structures of mtDNA required for efficient transcription from the first hea...
Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter
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Publisher
England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
Human mtDNA contains three promoters, suggesting a need for differential expression of the mitochondrial genome. Studies of mitochondrial transcription have used a reductionist approach, perhaps masking differential regulation. Here we evaluate transcription from light-strand (LSP) and heavy-strand (HSP1) promoters using templates that mimic their...
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Full title
Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter
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TN_cdi_doaj_primary_oai_doaj_org_article_4fc947bb6e7f428288930190d8f4385a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4fc947bb6e7f428288930190d8f4385a
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.27283
