Revisiting the inhibitory potential of protein kinase inhibitors against NEK7 protein via comprehens...
Revisiting the inhibitory potential of protein kinase inhibitors against NEK7 protein via comprehensive computational investigations
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The NEK7 protein is required for spindle formation, cell division, and the activation of the NLRP3 inflammasome receptor. The aberrant expression of NEK7 has been implicated to the growth of metastasis and severe inflammatory conditions like rheumatoid arthritis, liver cirrhosis, and gout. An emergent target for the development of anti-cancer drugs...
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Revisiting the inhibitory potential of protein kinase inhibitors against NEK7 protein via comprehensive computational investigations
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TN_cdi_doaj_primary_oai_doaj_org_article_4fcca5da20cd47f3acde2503b5dacab3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4fcca5da20cd47f3acde2503b5dacab3
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-31499-7
