Recombinant luciferase-expressing human cytomegalovirus (CMV) for evaluation of CMV inhibitors
Recombinant luciferase-expressing human cytomegalovirus (CMV) for evaluation of CMV inhibitors
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Recombinant Towne CMV expressing luciferase under the control of CMV-DNA polymerase (
POL
) or the late pp28 (UL99) promoters were evaluated for potential application in high-throughput screening of anti-viral compounds.
POL
-and pp28-luciferase displayed maximal expression 48 and 72 hours post infection, respectively. The pp28-lucifera...
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Full title
Recombinant luciferase-expressing human cytomegalovirus (CMV) for evaluation of CMV inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_4fce68f06fa447a9900416b8a0eff43d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4fce68f06fa447a9900416b8a0eff43d
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ISSN
1743-422X
E-ISSN
1743-422X
DOI
10.1186/1743-422X-8-40