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α-Klotho prevents diabetic retinopathy by reversing the senescence of macrophages

α-Klotho prevents diabetic retinopathy by reversing the senescence of macrophages

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4fe3dfbc42bc4af8a95a3f483673108e

α-Klotho prevents diabetic retinopathy by reversing the senescence of macrophages

About this item

Full title

α-Klotho prevents diabetic retinopathy by reversing the senescence of macrophages

Publisher

England: BioMed Central

Journal title

Cell communication and signaling, 2024-09, Vol.22 (1), p.449-19, Article 449

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus (DM) and a significant cause of acquired blindness in the working-age population worldwide. Aging is considered as an important risk factor for DR development. Macrophages in aged mice bear typical M2 marker proteins but simultaneously express a pro-inflammatory f...

Alternative Titles

Full title

α-Klotho prevents diabetic retinopathy by reversing the senescence of macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4fe3dfbc42bc4af8a95a3f483673108e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4fe3dfbc42bc4af8a95a3f483673108e

Other Identifiers

ISSN

1478-811X

E-ISSN

1478-811X

DOI

10.1186/s12964-024-01838-w

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