CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degrad...
CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation
About this item
Full title
Author / Creator
Quintanal-Villalonga, Alvaro , Kawasaki, Kenta , Redin, Esther , Uddin, Fathema , Rakhade, Swanand , Durani, Vidushi , Sabet, Amin , Shafer, Moniquetta , Karthaus, Wouter R. , Zaidi, Samir , Zhan, Yingqian A. , Manoj, Parvathy , Sridhar, Harsha , Kinyua, Dennis , Zhong, Hong , Mello, Barbara P. , Ciampricotti, Metamia , Bhanot, Umesh K. , Linkov, Irina , Qiu, Juan , Patel, Radhika A. , Morrissey, Colm , Mehta, Sanjoy , Barnes, Jesse , Haffner, Michael C. , Socci, Nicholas D. , Koche, Richard P. , de Stanchina, Elisa , Molina-Pinelo, Sonia , Salehi, Sohrab , Yu, Helena A. , Chan, Joseph M. and Rudin, Charles M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Neuroendocrine (NE) transformation is a mechanism of resistance to targeted therapy in lung and prostate adenocarcinomas leading to poor prognosis. Up to date, even if patients at high risk of transformation can be identified by the occurrence of Tumor Protein P53 (
TP53)
and Retinoblastoma Transcriptional Corepressor 1
(RB1)
mutations...
Alternative Titles
Full title
CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation
Authors, Artists and Contributors
Author / Creator
Kawasaki, Kenta
Redin, Esther
Uddin, Fathema
Rakhade, Swanand
Durani, Vidushi
Sabet, Amin
Shafer, Moniquetta
Karthaus, Wouter R.
Zaidi, Samir
Zhan, Yingqian A.
Manoj, Parvathy
Sridhar, Harsha
Kinyua, Dennis
Zhong, Hong
Mello, Barbara P.
Ciampricotti, Metamia
Bhanot, Umesh K.
Linkov, Irina
Qiu, Juan
Patel, Radhika A.
Morrissey, Colm
Mehta, Sanjoy
Barnes, Jesse
Haffner, Michael C.
Socci, Nicholas D.
Koche, Richard P.
de Stanchina, Elisa
Molina-Pinelo, Sonia
Salehi, Sohrab
Yu, Helena A.
Chan, Joseph M.
Rudin, Charles M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_501fe4c8a5e9423ca573e0d9f455d0b2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_501fe4c8a5e9423ca573e0d9f455d0b2
Other Identifiers
ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-024-01908-y