mcPGK1-dependent mitochondrial import of PGK1 promotes metabolic reprogramming and self-renewal of l...
mcPGK1-dependent mitochondrial import of PGK1 promotes metabolic reprogramming and self-renewal of liver TICs
About this item
Full title
Author / Creator
Chen, Zhenzhen , He, Qiankun , Lu, Tiankun , Wu, Jiayi , Shi, Gaoli , He, Luyun , Zong, Hong , Liu, Benyu and Zhu, Pingping
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Liver tumour-initiating cells (TICs) contribute to tumour initiation, metastasis, progression and drug resistance. Metabolic reprogramming is a cancer hallmark and plays vital roles in liver tumorigenesis. However, the role of metabolic reprogramming in TICs remains poorly explored. Here, we identify a mitochondria-encoded circular RNA, termed
m...
Alternative Titles
Full title
mcPGK1-dependent mitochondrial import of PGK1 promotes metabolic reprogramming and self-renewal of liver TICs
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5038c25814cc4671b195e3c1a40e4435
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5038c25814cc4671b195e3c1a40e4435
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-36651-5
