Postnatal DNA demethylation and its role in tissue maturation
Postnatal DNA demethylation and its role in tissue maturation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Development in mammals is accompanied by specific de novo and demethylation events that are thought to stabilize differentiated cell phenotypes. We demonstrate that a large percentage of the tissue-specific methylation pattern is generated postnatally. Demethylation in the liver is observed in thousands of enhancer-like sequences associated with ge...
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Full title
Postnatal DNA demethylation and its role in tissue maturation
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TN_cdi_doaj_primary_oai_doaj_org_article_50520c8d9e7d4a71beda66e83fbcd1e0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50520c8d9e7d4a71beda66e83fbcd1e0
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04456-6
