Log in to save to my catalogue

A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice

A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_506b5a2b20f3415e94f82e042797ec90

A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice

About this item

Full title

A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice

Publisher

Switzerland: MDPI AG

Journal title

Pharmaceutics, 2020-03, Vol.12 (3), p.284

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Alzheimer's disease (AD) is the leading cause of dementia. Non-competitive N-Methyl-D-aspartate (NMDA) receptor antagonist memantine improved cognition and molecular alterations after preclinical treatment. Nevertheless, clinical results are discouraging. In vivo efficacy of the RL-208, a new NMDA receptor blocker described recently, with favourabl...

Alternative Titles

Full title

A Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_506b5a2b20f3415e94f82e042797ec90

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_506b5a2b20f3415e94f82e042797ec90

Other Identifiers

ISSN

1999-4923

E-ISSN

1999-4923

DOI

10.3390/pharmaceutics12030284

How to access this item