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Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cance...

Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cance...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5070f645e7704c60bab1e06d4b70fcf1

Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells

About this item

Full title

Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2017-08, Vol.6

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

The urokinase receptor (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored protein that promotes tissue remodeling, tumor cell adhesion, migration and invasion. uPAR mediates degradation of the extracellular matrix through protease recruitment and enhances cell adhesion, migration and signaling through vitronectin binding and interactions with...

Alternative Titles

Full title

Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5070f645e7704c60bab1e06d4b70fcf1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5070f645e7704c60bab1e06d4b70fcf1

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.23649

How to access this item