Immune activation during pregnancy exacerbates ASD-related alterations in Shank3-deficient mice
Immune activation during pregnancy exacerbates ASD-related alterations in Shank3-deficient mice
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Publisher
England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Autism spectrum disorder (ASD) is mainly characterized by deficits in social interaction and communication and repetitive behaviors. Known causes of ASD are mutations of certain risk genes like the postsynaptic protein SHANK3 and environmental factors including prenatal infections.
To analyze the gene-environment interplay in ASD, we combined th...
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Full title
Immune activation during pregnancy exacerbates ASD-related alterations in Shank3-deficient mice
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TN_cdi_doaj_primary_oai_doaj_org_article_508bd4040ef242d8bc937e9009dc09be
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_508bd4040ef242d8bc937e9009dc09be
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ISSN
2040-2392
E-ISSN
2040-2392
DOI
10.1186/s13229-022-00532-3
