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Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidifica...

Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidifica...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50a7efdd53054d58bdc66c48775ef3ba

Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidification

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

ATP production requires the establishment of an electrochemical proton gradient across the inner mitochondrial membrane. Mitochondrial uncouplers dissipate this proton gradient and disrupt numerous cellular processes, including vesicular trafficking, mainly through energy depletion. Here we show that Endosidin9 (ES9), a novel mitochondrial uncouple...

Alternative Titles

Full title

Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidification

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_50a7efdd53054d58bdc66c48775ef3ba

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50a7efdd53054d58bdc66c48775ef3ba

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms11710