SAP130 released by damaged tubule drives necroinflammation via miRNA-219c/Mincle signaling in acute...
SAP130 released by damaged tubule drives necroinflammation via miRNA-219c/Mincle signaling in acute kidney injury
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Author / Creator
Lv, Lin-Li , Wang, Cui , Li, Zuo-Lin , Cao, Jing-Yuan , Zhong, Xin , Feng, Ye , Chen, Jun , Tang, Tao-Tao , Ni, Hai-Feng , Wu, Qiu-Li , Wang, Bin , Lan, Hui-Yao and Liu, Bi-Cheng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Tubules injury and immune cell activation are the common pathogenic mechanisms in acute kidney injury (AKI). However, the exact modes of immune cell activation following tubule damage are not fully understood. Here we uncovered that the release of cytoplasmic spliceosome associated protein 130 (SAP130) from the damaged tubular cells mediated necroi...
Alternative Titles
Full title
SAP130 released by damaged tubule drives necroinflammation via miRNA-219c/Mincle signaling in acute kidney injury
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_50af5ecc5f8d457b96f1414b614b6a16
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50af5ecc5f8d457b96f1414b614b6a16
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-04131-7
