Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens
Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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The malaria parasite Plasmodium falciparum and related apicomplexan pathogens contain an essential plastid organelle, the apicoplast, which is a key anti-parasitic target. Derived from secondary endosymbiosis, the apicoplast depends on novel, but largely cryptic, mechanisms for protein/lipid import and organelle inheritance during parasite replicat...
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Small molecule inhibition of apicomplexan FtsH1 disrupts plastid biogenesis in human pathogens
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TN_cdi_doaj_primary_oai_doaj_org_article_50caffaed1c243fd80d0b2e61f7ee1ab
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50caffaed1c243fd80d0b2e61f7ee1ab
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.29865
