Paclitaxel plus carboplatin and durvalumab with or without oleclumab for women with previously untre...
Paclitaxel plus carboplatin and durvalumab with or without oleclumab for women with previously untreated locally advanced or metastatic triple-negative breast cancer: the randomized SYNERGY phase I/II trial
About this item
Full title
Author / Creator
Buisseret, Laurence , Loirat, Delphine , Aftimos, Philippe , Maurer, Christian , Punie, Kevin , Debien, Véronique , Kristanto, Paulus , Eiger, Daniel , Goncalves, Anthony , Ghiringhelli, François , Taylor, Donatienne , Clatot, Florent , Van den Mooter, Tom , Ferrero, Jean-Marc , Bonnefoi, Hervé , Canon, Jean-Luc , Duhoux, Francois P. , Mansi, Laura , Poncin, Renaud , Barthélémy, Philippe , Isambert, Nicolas , Denis, Zoë , Catteau, Xavier , Salgado, Roberto , Agostinetto, Elisa , de Azambuja, Evandro , Rothé, Françoise , Craciun, Ligia , Venet, David , Romano, Emanuela , Stagg, John , Paesmans, Marianne , Larsimont, Denis , Sotiriou, Christos , Ignatiadis, Michail and Piccart-Gebhart, Martine
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Chemo-immunotherapy is the first-line standard of care for patients with PD-L1 positive metastatic triple-negative breast cancer (mTNBC). SYNERGY (NCT03616886) is a dose-finding phase I and a randomized phase II, open-label trial evaluating if targeting the immunosuppressive adenosine pathway can enhance the antitumor activity of chemo-immunotherap...
Alternative Titles
Full title
Paclitaxel plus carboplatin and durvalumab with or without oleclumab for women with previously untreated locally advanced or metastatic triple-negative breast cancer: the randomized SYNERGY phase I/II trial
Authors, Artists and Contributors
Author / Creator
Loirat, Delphine
Aftimos, Philippe
Maurer, Christian
Punie, Kevin
Debien, Véronique
Kristanto, Paulus
Eiger, Daniel
Goncalves, Anthony
Ghiringhelli, François
Taylor, Donatienne
Clatot, Florent
Van den Mooter, Tom
Ferrero, Jean-Marc
Bonnefoi, Hervé
Canon, Jean-Luc
Duhoux, Francois P.
Mansi, Laura
Poncin, Renaud
Barthélémy, Philippe
Isambert, Nicolas
Denis, Zoë
Catteau, Xavier
Salgado, Roberto
Agostinetto, Elisa
de Azambuja, Evandro
Rothé, Françoise
Craciun, Ligia
Venet, David
Romano, Emanuela
Stagg, John
Paesmans, Marianne
Larsimont, Denis
Sotiriou, Christos
Ignatiadis, Michail
Piccart-Gebhart, Martine
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_50f0c9a693404d0bbb0bf5ae3d4ee9c1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50f0c9a693404d0bbb0bf5ae3d4ee9c1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-42744-y
