Selective targeting of angiopoietin-like 3 (ANGPTL3) with vupanorsen for the treatment of patients w...
Selective targeting of angiopoietin-like 3 (ANGPTL3) with vupanorsen for the treatment of patients with familial partial lipodystrophy (FPLD): results of a proof-of-concept study
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England: BioMed Central
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English
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England: BioMed Central
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Familial partial lipodystrophy (FPLD) is a rare disease characterized by selective loss of peripheral subcutaneous fat, associated with dyslipidemia and diabetes mellitus. Reductions in circulating levels of ANGPTL3 are associated with lower triglyceride and other atherogenic lipids, making it an attractive target for treatment of FPLD patients. Th...
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Full title
Selective targeting of angiopoietin-like 3 (ANGPTL3) with vupanorsen for the treatment of patients with familial partial lipodystrophy (FPLD): results of a proof-of-concept study
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TN_cdi_doaj_primary_oai_doaj_org_article_50ffdd79d6e14f6093c4b51acb7bcb51
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_50ffdd79d6e14f6093c4b51acb7bcb51
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ISSN
1476-511X
E-ISSN
1476-511X
DOI
10.1186/s12944-021-01589-4
