In vitro safety evaluation of dopamine D3R antagonist, R-VK4-116, as a potential medication for the...
In vitro safety evaluation of dopamine D3R antagonist, R-VK4-116, as a potential medication for the treatment of opioid use disorder
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Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
R
-VK4-116 is currently being developed as a medication to treat opioid use disorder (OUD). To characterize
in vitro
safety properties of
R-
VK4-116, metabolic stability in hepatocytes or liver microsomes, metabolite identification, metabolism/transporter-mediated drug interactions, lysosomal perturbation, mitochondrial toxicity, off...
Alternative Titles
Full title
In vitro safety evaluation of dopamine D3R antagonist, R-VK4-116, as a potential medication for the treatment of opioid use disorder
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5111cddaef034d24a8c129d9b29b0f31
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5111cddaef034d24a8c129d9b29b0f31
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0315569
