Glycogen metabolism regulates macrophage-mediated acute inflammatory responses
Glycogen metabolism regulates macrophage-mediated acute inflammatory responses
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Author / Creator
Ma, Jingwei , Wei, Keke , Liu, Junwei , Tang, Ke , Zhang, Huafeng , Zhu, Liyan , Chen, Jie , Li, Fei , Xu, Pingwei , Chen, Jie , Liu, Jincheng , Fang, Haiqing , Tang, Liang , Wang, Dianheng , Zeng, Liping , Sun, Weiwei , Xie, Jing , Liu, Yuying and Huang, Bo
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Our current understanding of how sugar metabolism affects inflammatory pathways in macrophages is incomplete. Here, we show that glycogen metabolism is an important event that controls macrophage-mediated inflammatory responses. IFN-γ/LPS treatment stimulates macrophages to synthesize glycogen, which is then channeled through glycogenolysis to gene...
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Full title
Glycogen metabolism regulates macrophage-mediated acute inflammatory responses
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TN_cdi_doaj_primary_oai_doaj_org_article_5147ac64c2054a77adfffdcb6f32df95
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5147ac64c2054a77adfffdcb6f32df95
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15636-8
