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PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of...

PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5169246f34c04f48978b5469fb899c63

PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of reduced survival in patients

About this item

Full title

PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of reduced survival in patients

Publisher

United States: John Wiley & Sons, Inc

Journal title

Molecular oncology, 2024-10, Vol.18 (10), p.2471-2494

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Paired related homeobox 1 (PRRX1) is an inducer of epithelial‐to‐mesenchymal transition (EMT) in different types of cancer cells. We detected low PRRX1 expression in nevus but increased levels in primary human melanoma and cell lines carrying the BRAFV600E mutation. High expression of PRRX1 correlates with invasiveness and enrichment of genes belon...

Alternative Titles

Full title

PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of reduced survival in patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5169246f34c04f48978b5469fb899c63

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5169246f34c04f48978b5469fb899c63

Other Identifiers

ISSN

1574-7891,1878-0261

E-ISSN

1878-0261

DOI

10.1002/1878-0261.13688

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