Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induce...
Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity
About this item
Full title
Author / Creator
Dávalos-Salas, Mercedes , Montgomery, Magdalene K. , Reehorst, Camilla M. , Nightingale, Rebecca , Ng, Irvin , Anderton, Holly , Al-Obaidi, Sheren , Lesmana, Analia , Scott, Cameron M. , Ioannidis, Paul , Kalra, Hina , Keerthikumar, Shivakumar , Tögel, Lars , Rigopoulos, Angela , Gong, Sylvia J. , Williams, David S. , Yoganantharaja, Prusoth , Bell-Anderson, Kim , Mathivanan, Suresh , Gibert, Yann , Hiebert, Scott , Scott, Andrew M. , Watt, Matthew J. and Mariadason, John M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Histone deacetylase 3
(
Hdac3
) regulates the expression of lipid metabolism genes in multiple tissues, however its role in regulating lipid metabolism in the intestinal epithelium is unknown. Here we demonstrate that intestine-specific deletion of
Hdac3
(
Hdac3
IKO
) protects mice from diet induced obesity. Intestinal epith...
Alternative Titles
Full title
Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity
Authors, Artists and Contributors
Author / Creator
Montgomery, Magdalene K.
Reehorst, Camilla M.
Nightingale, Rebecca
Ng, Irvin
Anderton, Holly
Al-Obaidi, Sheren
Lesmana, Analia
Scott, Cameron M.
Ioannidis, Paul
Kalra, Hina
Keerthikumar, Shivakumar
Tögel, Lars
Rigopoulos, Angela
Gong, Sylvia J.
Williams, David S.
Yoganantharaja, Prusoth
Bell-Anderson, Kim
Mathivanan, Suresh
Gibert, Yann
Hiebert, Scott
Scott, Andrew M.
Watt, Matthew J.
Mariadason, John M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_517f7ab37ce74aff9258c9ede119de9a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_517f7ab37ce74aff9258c9ede119de9a
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13180-8
