Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice
Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice
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Author / Creator
Ni, You , Feng, Yifan , Shen, Dingding , Chen, Ming , Zhu, Xiaona , Zhou, Qinming , Gao, Yining , Liu, Jun , Zhang, Qi , Shen, Yuntian , Peng, Lisheng , Zeng, Zike , Yin, Dou , Hu, Ji and Chen, Sheng
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Anti-IgLON5 disease is a rare neurological disorder associated with autoantibodies against the neuronal cell adhesion protein, IgLON5. Cellular investigations with human IgLON5 antibodies have suggested an antibody-mediated pathogenesis, but whether human IgLON5 autoantibodies can induce disease symptoms in mice is yet to be shown. Moreover, the ef...
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Full title
Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5195a919dfe843c28f3be7daf9b4dee0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5195a919dfe843c28f3be7daf9b4dee0
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-022-02520-z
