Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS
Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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We present long-read Tet-assisted pyridine borane sequencing (lrTAPS) for targeted base-resolution sequencing of DNA methylation and hydroxymethylation in regions up to 10 kb from nanogram-level input. Compatible with both Oxford Nanopore and PacBio Single-Molecule Real-Time (SMRT) sequencing, lrTAPS detects methylation with accuracy comparable to...
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Full title
Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS
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TN_cdi_doaj_primary_oai_doaj_org_article_51a16a1b45b7443391655c421790aeea
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_51a16a1b45b7443391655c421790aeea
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ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-020-01969-6
