Citrullinated myelin induces microglial TNFα and inhibits endogenous repair in the cuprizone model o...
Citrullinated myelin induces microglial TNFα and inhibits endogenous repair in the cuprizone model of demyelination
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Publisher
England: BioMed Central
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Language
English
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England: BioMed Central
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Contents
Microglia are the primary phagocytes of the central nervous system and are responsible for removing damaged myelin following demyelination. Previous investigations exploring the consequences of myelin phagocytosis on microglial activation overlooked the biochemical modifications present on myelin debris. Such modifications, including citrullination...
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Full title
Citrullinated myelin induces microglial TNFα and inhibits endogenous repair in the cuprizone model of demyelination
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TN_cdi_doaj_primary_oai_doaj_org_article_51cf6a9e5ba6479ca532c06010660dc7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_51cf6a9e5ba6479ca532c06010660dc7
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-021-02360-3
