Effects of temporal IFNγ exposure on macrophage phenotype and secretory profile: exploring GMP-Compl...
Effects of temporal IFNγ exposure on macrophage phenotype and secretory profile: exploring GMP-Compliant production of a novel subtype of regulatory macrophages (Mreg IFNγ0 ) for potential cell therapeutic applications
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Macrophages are involved in tissue homeostasis, angiogenesis and immunomodulation. Proangiogenic and anti-inflammatory macrophages (regulatory macrophages, Mreg) can be differentiated in-vitro from CD14
monocytes by using a defined cell culture medium and a stimulus of IFNγ.
To scrutinize the potential impact of temporal IFNγ exposure on macr...
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Full title
Effects of temporal IFNγ exposure on macrophage phenotype and secretory profile: exploring GMP-Compliant production of a novel subtype of regulatory macrophages (Mreg IFNγ0 ) for potential cell therapeutic applications
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TN_cdi_doaj_primary_oai_doaj_org_article_51f12bd03bc74df9971446b0755322a3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_51f12bd03bc74df9971446b0755322a3
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ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-024-05336-y
