Activation of cAMP (EPAC2) signaling pathway promotes hepatocyte attachment
Activation of cAMP (EPAC2) signaling pathway promotes hepatocyte attachment
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Primary Human Hepatocyte (PHH) remains undefeated as the gold standard in hepatic studies. Despite its valuable properties, partial attachment loss due to the extraction process and cryopreservation remained the main hurdle in its application. We hypothesized that we could overcome the loss of PHH cell attachment through thawing protocol adjustment...
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Activation of cAMP (EPAC2) signaling pathway promotes hepatocyte attachment
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TN_cdi_doaj_primary_oai_doaj_org_article_51fa1f23ba6a491b8fe53b6bf32dd11c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_51fa1f23ba6a491b8fe53b6bf32dd11c
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-39712-3
