Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and...
Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations
About this item
Full title
Author / Creator
Nanni, Patrizia , Landuzzi, Lorena , Manara, Maria Cristina , Righi, Alberto , Nicoletti, Giordano , Cristalli, Camilla , Pasello, Michela , Parra, Alessandro , Carrabotta, Marianna , Ferracin, Manuela , Palladini, Arianna , Ianzano, Marianna L. , Giusti, Veronica , Ruzzi, Francesca , Magnani, Mauro , Donati, Davide Maria , Picci, Piero , Lollini, Pier-Luigi and Scotlandi, Katia
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Standard therapy of osteosarcoma (OS) and Ewing sarcoma (EW) rests on cytotoxic regimes, which are largely unsuccessful in advanced patients. Preclinical models are needed to break this impasse. A panel of patient-derived xenografts (PDX) was established by implantation of fresh, surgically resected osteosarcoma (OS) and Ewing sarcoma (EW) in NSG m...
Alternative Titles
Full title
Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations
Authors, Artists and Contributors
Author / Creator
Landuzzi, Lorena
Manara, Maria Cristina
Righi, Alberto
Nicoletti, Giordano
Cristalli, Camilla
Pasello, Michela
Parra, Alessandro
Carrabotta, Marianna
Ferracin, Manuela
Palladini, Arianna
Ianzano, Marianna L.
Giusti, Veronica
Ruzzi, Francesca
Magnani, Mauro
Donati, Davide Maria
Picci, Piero
Lollini, Pier-Luigi
Scotlandi, Katia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_520fd06572ac4ed78a2083b0e3a1fa0d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_520fd06572ac4ed78a2083b0e3a1fa0d
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-019-48634-y
