Structural Insights into the Regulation Mechanism of Small GTPases by GEFs
Structural Insights into the Regulation Mechanism of Small GTPases by GEFs
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Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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Contents
Small GTPases are key regulators of cellular events, and their dysfunction causes many types of cancer. They serve as molecular switches by cycling between inactive guanosine diphosphate (GDP)-bound and active guanosine triphosphate (GTP)-bound states. GTPases are deactivated by GTPase-activating proteins (GAPs) and are activated by guanine-nucleot...
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Full title
Structural Insights into the Regulation Mechanism of Small GTPases by GEFs
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TN_cdi_doaj_primary_oai_doaj_org_article_5210b944f3e54fee81efe0fd2d404071
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5210b944f3e54fee81efe0fd2d404071
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules24183308
